The history of using drones for pesticide application in agriculture dates back to the 1980s. However, the potential application of drones in agriculture gained media attention in the 2010s. This article categorizes and introduces various types of drones, regulations for drones in Iran, prevalent drones in Iran, leading companies in drone technology, the application of drone technology in weed science, opportunities and challenges of this technology, and research needs for appropriate usage of drone technology in the weed science discipline. The primary objective was to address the question of whether the broadcast application of herbicides via drones is scientifically sound. drone technology has numerous applications in weed science, including identifying weed infestations and invasive plants, evaluating damage caused by herbicides to crops, identifying and monitoring herbicide-resistant weeds, patch-spraying of herbicides, monitoring invasive plants, and assessing the competitive ability of weeds. Nevertheless, the effectiveness of drone-based broadcast application of herbicides faces uncertainties and questions due to its characteristics compared to ground-based sprayers, such as volume of solution, flight speed, flight altitude, as well as the lack of appropriate information and guidelines regarding the application of this technology. Consequently, the use of drone-based broadcast application of herbicides is not currently endorsed by the scientific authorities in Iran. Therefore, it is essential to conduct further research to assess the impact of factors such as the carrier volume of water, nozzle type, flight altitude, flight speed, weather conditions including temperature and wind speed, as well as the type of herbicide on the efficacy of drone sprayers. Subsequently, standardized guidelines should be developed for the application or non-application of each herbicide using drone sprayers.